The molecular features of normal and atopic dermatitis skin in infants, children, adolescents, and adults
Y Renert-Yuval, E Del Duca, AB Pavel, M Fang… - Journal of Allergy and …, 2021 - Elsevier
Background Although atopic dermatitis (AD) often presents in infancy and persists into
adulthood, comparative characterization of AD skin among different pediatric age groups is
lacking. Objective We sought to define skin biopsy profiles of lesional and nonlesional AD
across different age groups (0-5-year-old infants with disease duration< 6 months, 6-11-year-
old children, 12-17-year-old adolescents,≥ 18-year-old adults) versus age-appropriate
controls. Methods We performed gene expression analyses by RNA-sequencing and real …
adulthood, comparative characterization of AD skin among different pediatric age groups is
lacking. Objective We sought to define skin biopsy profiles of lesional and nonlesional AD
across different age groups (0-5-year-old infants with disease duration< 6 months, 6-11-year-
old children, 12-17-year-old adolescents,≥ 18-year-old adults) versus age-appropriate
controls. Methods We performed gene expression analyses by RNA-sequencing and real …
